Role of cis - acting sites in stimulation of the phage 4 λ P RM promoter by CI - mediated looping
نویسندگان
چکیده
* Corresponding author: 17 Department of Molecular and Cellular Biology, University of Arizona 18 Life Sciences South Building, 1007 Lowell Street, Tucson, AZ 85721 19 Phone: (520) 621-5629 20 Fax: (520) 621-3709 21 Email: [email protected] 22 23 Copyright © 2013, American Society for Microbiology. All Rights Reserved. J. Bacteriol. doi:10.1128/JB.02148-12 JB Accepts, published online ahead of print on 24 May 2013
منابع مشابه
Role of cis-acting sites in stimulation of the phage λ P(RM) promoter by CI-mediated looping.
The lysogenic state of phage λ is maintained by the CI repressor. CI binds to three operators each in the right operator (O(R)) and left operator (O(L)) regions, which lie 2.4 kb apart. At moderate CI levels, the predominant binding pattern is two dimers of CI bound cooperatively at each regulatory region. The resulting tetramers can then interact, forming an octamer and a loop of the interveni...
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